HLA-DPB1 Compatibility Wizard

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0 of 5. Select the reagent lot (this determines which beads are in the panel).

This application is currently using SAB alleles contained in the following two (2) panels:

1. LABScreen Single Antigen HLA Class II - Group 1 (various lots) [LS2A01]
2. LABScreen Single Antigen HLA Class II Supplement (various lots) [LS2ASP01]

The supplemental panel alleles may not be used, depending on which reagent lot is selected.

  
FOR RESEARCH USE ONLY
session ID:
IMGT allele database version:
single antigen bead (SAB) reagent lot number:
source code
Copyright © 2018, Geoffrey H. Smith, MD

HLA-DPB1 Compatibility Wizard

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1 of 5. Select the RECIPIENT's HLA-DPB1 type.

Allele #1: not selected

Allele #2: not selected

  
FOR RESEARCH USE ONLY
session ID:
IMGT allele database version:
single antigen bead (SAB) reagent lot number:
source code
Copyright © 2018, Geoffrey H. Smith, MD

HLA-DPB1 Compatibility Wizard

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2 of 5. Select the recipient's HLA-DPB1 antibodies (positive single antigen beads).

Reactivity for an HLA-DPB1 epitope is predicted when all of the beads bearing that epitope are positive, unless the epitope is present on any of the recipient's HLA-DPB1 alleles.

  
FOR RESEARCH USE ONLY
session ID:
IMGT allele database version:
single antigen bead (SAB) reagent lot number:
source code
Copyright © 2018, Geoffrey H. Smith, MD

HLA-DPB1 Compatibility Wizard

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3 of 5. Select any HLA-DPB1 epitopes for which the recipient has known HLA-DPB1 antibodies.

Any HLA-DPB1 epitopes selected here are added to the set of reactive epitopes predicted from bead positivity in the previous step, unless the epitope is present on any of the recipient's HLA-DPB1 alleles.

  
FOR RESEARCH USE ONLY
session ID:
IMGT allele database version:
single antigen bead (SAB) reagent lot number:
source code
Copyright © 2018, Geoffrey H. Smith, MD

HLA-DPB1 Compatibility Wizard

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4 of 5. Select the DONOR's HLA-DPB1 type.

Allele #1: not selected

Allele #2: not selected

  
FOR RESEARCH USE ONLY
session ID:
IMGT allele database version:
single antigen bead (SAB) reagent lot number:
source code
Copyright © 2018, Geoffrey H. Smith, MD

HLA-DPB1 Compatibility Wizard

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5 of 5. Here is the HLA-DPB1 compatibility report for this recipient and donor.

Compatibility predictions are based on the union of the user-specified epitopes and the predicted epitopes, and automatically exclude epitopes that are present on any of the recipient's own alleles.

Recipient Allele #1:
Recipient Allele #2:

Recipient Antibodies (positive SABs):

Reactive Recipient Epitopes (user-specified):
Reactive Recipient Epitopes (predicted from positive SABs):

Donor Allele #1:
Donor Allele #2:

All HLA-DPB1 alleles by compatibility:

Incompatible
Learn more		 Electronically
Incompatible
Learn more		 Not Electronically
Incompatible
Learn more		 Autoantibody
Learn more

The single antigen bead corresponding to this allele is positive.

This allele has an epitope which is likely to be reactive with recipient antibodies.

This allele is not listed in any of the other categories and is likely to be compatible with the recipient.

The single antigen bead corresponding to this allele is positive, but it is also a recipient allele.

  
FOR RESEARCH USE ONLY
session ID:
IMGT allele database version:
single antigen bead (SAB) reagent lot number:
source code
Copyright © 2018, Geoffrey H. Smith, MD